Topic: Cancer biology

It can be strange to think of cancer cells not dividing, but sleeping cancer cells could help to explain why some cancers come back after treatment.

New lung cancer research shows that detecting potential tumour cells leaving the vein in the lung at surgery may predict the diseases return.

Cancer treatments can work in lots of different ways, aiming to kill tumour cells or keep them under control. Ideally they cause tumours to shrink, but they can also be considered successful if they stop tumours growing. But unfortunately, the effects don’t always last forever.

Scientists have developed an entirely new way to look at tumours. And it’s helped them solve the mystery of how some pancreatic tumours develop.

Anh Hoang Le, a PhD student at the Cancer Research UK Beatson Institute in Glasgow, studies two proteins that we know curiously little about: CYRI-A and CYRI-B.

We look at the research made possible by people who donate their bodies after their death, including helping scientists understand how advanced cancers spread.

It’s hard to talking about cancers ‘knowing’ something, but they can have predictable patterns of spread. And scientists are beginning to understand why.

Our international team of scientists are tackling a fundamental question about how cancer develops: why do some gene faults only cause cancer in certain organs?

Inflammation can prevent infections and helps repair injuries. But for people with long-term inflammatory conditions, it can sometimes lead to cancer.

Gut bacteria may help some bowel cancers grow. Our Grand Challenge scientists want to see if tinkering with these tiny communities could be a new way to treat cancer.