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With our appetite for low or zero sugar products increasing, artificial sweeteners are big business.

Food or drinks containing artificial sweeteners are often marketed as a healthier option, and it’s understandable why. Because artificial sweeteners are significantly sweeter than sugar, they can be used in very small amounts and contribute little to no calories. There are lots of types, but the most well researched are aspartame and saccharin.

A possible link between artificial sweeteners and cancer has been reported in the media. But despite lots of research in this area, there’s no convincing evidence that sweeteners in our food and drink increase the risk of cancer.

While there’s nothing to worry about from a cancer perspective, questions still remain about whether or not artificial sweeteners can help us lose weight. And as being overweight or obese increases the risk of 13 types of cancer, knowing whether they help is important.

But getting a solid answer to this question is tricky. Diet is notoriously difficult to study and so far, researchers have reached different conclusions. Overall, it looks like artificial sweeteners like aspartame aren’t causing harm, but they’re not having the big weight loss benefits that some people expected either.

Can we have our cake and eat it too?

If sweeteners are replacing a high calorie alternative, it seems logical that by reducing calories they should help with weight loss.

But whether this is the case is tricky to prove. It’s difficult to study the long-term impact of a specific part of our diet for lots of reasons. For one, measuring exactly how much people consume is hard. And there are lots of other things that could explain any differences – like other elements of a person’s diet or how much they exercise – so we need large studies that take these things in to account.

Most studies have looked at artificially sweetened drinks rather than sweeteners in foods, and the results are mixed. For this reason, the European Food Safety Authority won’t allow products containing artificial sweeteners to carry a weight loss health claim.

A 2016 review found that people using artificial sweeteners had both a lower calorie intake and reduced body weight. But these results should be treated with a healthy dose of scepticism as the study was conducted and funded by the International Life Sciences Institute, whose members include companies such as Coca-Cola, Red Bull and Pepsi. Each of these companies has a vested interested in the artificial sweetener business.

The results also don’t fully tally up with a more recent, independent analysis of 56 studies. This analysis found very little evidence to suggest low energy artificial or natural sweeteners, like stevia, are helping lots of people to lose weight.

But when 3 studies were picked out that only included overweight or obese adults, artificial sweeteners did provide a small benefit to weight loss. While positive for this group of people, the researchers say that larger and longer-term studies are needed to confirm this.

If not weight loss, then what about weight gain?

Surprisingly, some research has found that sweeteners might make us gain weight. But the latest review didn’t agree with this.

This raises an important question: if products containing artificial sweeteners contain less calories, why doesn’t the evidence show they are helping us to lose weight?

One explanation is something called ‘reverse causality’ – whereby people who are already overweight or obese are more likely to be choosing food or drinks with sweeteners to help with weight loss. This makes it difficult to say whether the artificial sweeteners or weight gain came first, or how one may affect the other.

But some researchers think there might be more going on, including effects on our gut health, appetite and desire for sweet foods.

But these are unproven theories.

Are sweeteners actually making us hungrier?

Throughout the day, our gut sends messages to our brain in the form of hormones. These hormones tell our brain when we are hungry or full. There has been some suggestion that sweeteners could interfere with these messages, and therefore make us eat more rather than less.

‘’When we eat food containing sugar, the gut produces more of the hormone that tells our brain we are full, and less of the hormone that tells our brain we are hungry. Currently, the evidence suggests that sweeteners don’t prompt the release of either of these gut hormones in humans,’ says Dr Ana Pinto, a nutrition researcher from King’s College London (KCL).

Does a diet or low-calorie option at lunch equal more at dinner?

If sweeteners aren’t affecting our gut, is there a psychological effect?

Some research has proposed a reward effect, in which we feel we have some ‘calories to spare’ if we have replaced a high calorie product with a diet alternative.

Daphne Katsikioti, who also studies nutrition at KCL, explains: “‘Some researchers have suggested that when we eat or drink products containing artificial sweeteners, we later compensate for the ‘missing’ energy by eating more.”

But she adds that there’s good evidence to suggest that this doesn’t happen and that artificial sweeteners can be helpful to reduce calories.

Finally, some people have suggested that the intense sweetness that comes from sweeteners could lead to a particularly sweet tooth in the long term. The latest review found very little evidence of this, so more research is needed to pin down if this a possible side effect of artificial sweeteners.

To sweeten or not to sweeten?

Despite the theories, the European Food Safety Authority have ruled that artificial sweeteners in food and drink pose no threat to our health if consumed within daily allowances. For aspartame, this is equivalent to 15 cans of diet coke. That’s a stark contrast to what we know about the harms of having too much sugar.

But products containing sweeteners often don’t offer much nutritional benefit. And the lack of convincing evidence that they can help with weight loss shouldn’t be overlooked.

The take-home message is artificially sweetened drinks aren’t a silver bullet for weight loss. But if you drink a lot of sugary drinks and think a diet version might help you cut down on sugar, that’s a good step and is very unlikely to do you any harm.

Katie Patrick is a health information officer at Cancer Research UK 


Jill Stroud February 16, 2019

Can’t agree that Aspartame can do no harm; believe in USA it is banned!
Better to have natural unrefined sugar and control intake. There are far too many artificial sweeteners, should stick to natural sweeteners and be more disciplined on consumption of sugary drinks

Don February 16, 2019

I have used Artificial sweeteners & sugar free soft drinks for about 25 years no problems, as for weight loss just cut down on food intake & excercise a little every day thats been my only change and have lost 2st in 11 month.

Peter February 16, 2019

Artificial sweeteners are bad for health, there is a proven link to MS and Fibromyalgia.

Big corporations only use them to maximise profits using cheap and nasty altered ingredients.

Because of the sugar tax, now many other companies are adopting this awful practice and litterally poisoning people with chemically altered sugars.

The massive health implications pertaining to cancer may not yet be known. Just because you did not find something now, it does not mean you won’t find a link many years later after a great deal of damage has been done to health.

Also, artificial sugars interfere with the body’s ability to break down fats. Therefore, drinks with artificial sweeteners actually cause weight gain in all the wrong places in the body as the fats that can’t be processed have to be stored somewhere.

Eva Wye February 16, 2019

I find it quite shocking that Cancer Research UK is saying that diet coke and aspartame is not unhealthy. Yes, diet is very difficult to research, that is why I find this findings a bit biased. Are perhaps the artificial sweeteners companies funding the research? It is well known that cancer can feed on sugar. It also makes common sense that sugar and artificial sweeteners are BAD for our health. The same as pesticides in our food and harmful toxic ingredients in our beauty products.

Deborah Douglas February 16, 2019

I certainly don’t shy away from anything artificial, have just made a fresh raspberry, mascarpone and chocolate cheesecake, but the base was packet of Green’s cheesecake mix. Sorry if you think I was having a go, was just saying everything in moderation is probably fine. I just don’t like taste of these sweeteners but fine for people who do.

Audrey February 16, 2019

My husband and I have used sweeteners in tea and coffee for most of our lives (we are both 84). Neither of us is obese. I hate to think how many spoonfuls of sugar we would be having a day if we didn’t use sweeteners!

Tom February 16, 2019

Fascinating! I think health-conscious folk tend to shy away from anything “artificial”… Your comments make me less afraid of consuming these products.

Deborah Douglas February 16, 2019

I think moderation/variation is the key to good health and eating mainly unprocessed foods if possible and drinking plenty of water. I am not a fan of artificial sweeteners, but recognise they may have a place for some people.

Susan Perryman February 16, 2019

The aspartame upsets my bladder.

Frances February 16, 2019

I read somewhere that aspatume is bad for
your bones I have osteoarthritis so try to control my weight but avoid anything with aspatume in not easy but it can be done.

Rosanne Eden February 16, 2019

I am most surprised that you even mention diet coke, as this product is often used to clean kettles, engine parts and coins. As a four time victim of cancer, now clear, I would not use any type of artificial sweetener or chemical product in my body. I think all products that use any type of artificial agent or chemical should have this fact boldly displayed on the front of the packaging. I do not use sugar either.

Elaine February 16, 2019

I find that artificial sweeteners can help people lose weight as long as they are taken in moderation. I have had to change to sweeteners as I now have type 2 diabetes. I have lost nearly 2 stone but this down to a combination of reducing my portion size, eating less carbohydrates & using sweeteners . I feel healthier for it, I don’t feel as hungry as a result of using them but you have to exercise as well if you want to lose weight as just taking sweeteners do it.

Dee February 16, 2019

There’s no place in food for artificial sweeteners

Douglas Blow February 16, 2019

Just cut down on sugar intake, excercise more.

Adrianna February 15, 2019

I stop drinking regular coke and switched to come zero. Drink the same amount and did loose weight. It doesn’t make me hungry at all. Funny thing that my sister is exactly opposite. She feels more hungry after drinking something with sweeteners.

Mary February 15, 2019

the taste of many artificial sweeteners is so horrible that I don’t buy items containing them.
Many drinks say ”no added sugar, no artificial colours or flavourings ” but neglect to say that they contain artificial sweeteners

Lloyd Halasz February 15, 2019

I hate using sweetener because it gives me a very dodgy stomach and I find I have dreadful out of control wind that goes down.

Maureen Young February 15, 2019

Interesting article. I was trying to lose weight a while ago and changed to artificial sweeteners. When I had a blood test I was informed that I was borderline diabetic. The only change in my diet was the artificial sweeteners. I stopped using them and my next blood test was normal. I would never use them again.

Roz February 15, 2019

I don’t like artificially seeetened drinks, yogurts etc. I find they have an aftertaste in my mouth. Prefer to eat more natural food but just eat less. My cats enjoy licking the yogurt pot when I have finished, but don’t like Mullerlight yogurts that my husband eats.

Kevin Jones February 15, 2019

Informative article – thank you.

Michael February 15, 2019

I find different sweeteners have different effect with me. Canderal is the worst with hunger, thirst and weight gain.

Lorraine Holmes February 15, 2019

I have heard that sweeteners make you more hungry and aspartame isn’t good for you anything artificial isn’t good for you? I have stopped putting sugar in my tea and coffee, I don’t use artificial sweeteners

Mahima February 15, 2019

Thank you so much for sharing recipes.Great blog!!!

Max February 13, 2019

This info is really very good .Every one must know about this