Trial success helps patients avoid radical bladder cancer surgery

Wendy Powell

Wendy Powell took part in the early clinical trial

Last week we reported on the success of a major bladder cancer trial, funded by Cancer Research UK.

The practice-changing trial will mean that, in future, fewer of the thousands of patients diagnosed with the disease each year will need their bladder removed, and, in some cases, their womb and ovaries or prostate and urethra too (since these are the areas where the cancer is most likely to return).

Removing the bladder is a major operation with implications for the rest of a patient’s life. As the disease is linked to smoking and around eight out of ten cases diagnosed in patients over 65, some patients are in relatively poor general health when diagnosed and so unable to cope with such radical surgery.

Until recently the only alternative has been radiotherapy. But around a third of patients given radiotherapy eventually relapse with invasive disease and so need to have their bladder removed anyway.

To try to improve things, researchers based at the University of Birmingham and The Institute for Cancer Research in Sutton, funded by Cancer Research UK, have been looking for better alternatives.

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News digest – landmark breast cancer study, bladder cancer, plain packaging of cigarettes, and more

News

Lots in the news this week

  • A major Cancer Research UK study published this week could revolutionise the way women with breast cancer are diagnosed and treated in the future. It reclassifies the disease into 10 completely new categories based on their genetic make-up. We’ve got an extensive analysis of the paper on the blog. And watch our chief executive Harpal Kumar and study leader Carlos Caldas talk about the implications of the study.
  • Another big study funded by us – this time a bladder cancer trial – showed that patients given low doses of chemotherapy with radiotherapy are nearly 50 per cent less likely to relapse with the most lethal form of the disease compared to those given radiotherapy alone. This could mean fewer patients need their bladder removed and provides an alternative for frailer patients who are too weak for surgery. Continue reading

Annual Review 2010/11 – Clinical trials: testing treatments that save lives

Woman on a clinical trial

Clinical trials are crucial in cancer research

Since 1995, more than 100,000 patients have taken part in our treatment trials.

In this final article selected from our Annual Review, we focus on the crucial role of clinical trials and the people who take part in them.

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No need to worry about having a shower or drinking water

A woman swimming

Going for a swim won't give you cancer

Swimming too often in chlorinated water ‘could increase risk of developing bladder cancer’, claim scientists”.

But did they, or is this another example of misreporting cancer research by the media?

Unfortunately, it’s the latter. This is an example of poor reporting, which makes unwarranted claims about human health. The research itself says nothing new about bladder cancer, and didn’t even involve people with the disease.

Let’s have a look at what’s going on.

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