Bill Bryson: notes from a non-scientist

In one of our boldest steps yet in our fight against cancer we’ve pledged to raise £100million to support the building of the Francis Crick Institute. The Crick, set to be one of the largest biomedical research centres in Europe, will benefit millions of people – not only cancer patients but also those suffering from other illnesses such as heart and neurodegenerative disease. But in order to make this happen we need the support of generous philanthropists.

And is why last week we held the first in a series of science lectures we’ll be running at the Wellcome Trust collection in London. Its focus was on how remarkable scientific breakthroughs can be made when scientists who work on a range of different areas and diseases work together with each other.

These benefits of scientific collaboration must not be underestimated. As Professor Sir Paul Nurse, who hosted the talk, said, it was the combination of biology and physics that brought about the discovery of the structure of the DNA double helix – one of the greatest scientific breakthroughs of our time.

On the night, we were thrilled to have the American bestselling author Bill Bryson speaking, who’s most famous for his novels ‘Notes from a Small Island’ and more recently ‘A Short History of Nearly Everything’. You can watch his talk here:

Bill talked of his amazement at the levels of dedication scientists will go to in their work. He had the night before met a geo-chemist who was about to leave for a remote location in Antarctica for up to six weeks. The researcher goes to measure the rate the glacier is melting to increase their understanding of climate change.

Bill asked him: “What’s it like to spend three months with another guy in a tent?”

The scientist replied; “It’s friggin awful! It’s just a nightmare. No matter how decent and considerate and wonderful the other person is and how hard you try to be like that yourself it’s impossible for two human beings to stay together for that long a period without there being friction… it’s especially bad when the weather closes in and you’re stuck in a tent for days at a time.”

Bill was amazed that anyone would go year after year to the most remote and bleak of situations knowing it would be awful. He said:

“It gave me a moment of clarity about what scientists do. I could never do that. I don’t know anyone in my sphere of life who would. I don’t know any writer who would go and spend three months in a tent with a stranger at a time just to gather another morsel of information for the sake of humanity. I don’t know any historians who would, or lawyers or accountants. But I do know many scientists who would.”

The event was thoroughly engaging and the audience would most certainly have left with a new found respect for the wonders of science. We can now look forward to the second in the series next Spring.

Cancer is the biggest premature killer

Despite tremendous progress against cancer in recent decades, the disease remains a huge health challenge in the UK. Only last week, our Chief Executive Harpal Kumar warned that the NHS faces a “perfect storm” of rising cancer cases and squeezed finances over the next 20 years.

Today we’ve released further figures that serve as a stark reminder of the scale of the challenge we face. On average most men in the UK will live until their late 70s and women until their early 80s. But our latest report shows that cancer is now responsible for killing 40 per cent of all the men and women who die before their time between the ages of 25 and 74.

The 4 Most Common Causes of Death, Percentages of All Deaths, 25-74, UK, 2007-2009

In other words, 4 in every 10 people in this age group who die before they reach their life expectancy are killed by cancer.

Our chief clinician, Professor Peter Johnson explains more in this video:

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Flora’s story shows how our vital research is beating cancer

An image of Flora Skeates

Survivor Flora Skeates and her family

Flora Skeates knows only too well the difference that cancer research makes. Diagnosed with bowel cancer when she was just 28, her treatment involved the drug oxaliplatin – a drug that our scientists played a key role in developing.

She’s now representing Cancer Research UK in a photo that’s part of the ‘Legacies Through A Lens’ exhibition in London, highlighting the importance of legacies – donations left in wills – in raising money for charities.

Around a third of the money we spend on our research comes from generous gifts left by people in their wills, so it’s a good opportunity to explore how the hard work of our scientists and doctors led to Flora’s treatment.

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Making a impact in rarer cancers – the ABC02 trial


A patient and a nurse

Clinical trials lead to improvements in cancer treatment

Finding new treatments for rare and hard-to-treat cancers is one of our greatest challenges.

The best way of testing out new or improved treatments is to run a clinical trial, involving as many patients as possible, to compare the potentially better option with the best current treatment.

A team of Cancer Research UK-funded scientists has done just this, to assess the merits of a new treatment method for advanced gall bladder and bile duct cancer that can’t be operated on.

These cancers together affect fewer than 2,000 people per year in the UK, making trials harder to run. As a result, doctors only had limited evidence on which to base treatment decisions.

To help improve this situation, the Cancer Research UK-funded team have carried out the largest ever large-scale clinical trial for these cancers, which are difficult to treat successfully. The trial, called ABC02, was run by Cancer Research UK and the UCL Clinical Trials Centre.

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Show your support for sunbed legislation

Nicola Roberts, Julie Morgan and Andy Burnham

Singer Nicola Roberts, Julie Morgan MP and Andy Burnham MP

Today in Parliament we held a briefing for MPs to kick start Julie Morgan’s bid to take forward a Private Member’s Bill on sunbeds, which would protect children and teenagers from the dangers of sunbeds.

The Rt Hon Andy Burnham MP, Secretary of State for Health, came to show his support along with Nicola Roberts from Girls Aloud who is presenting a documentary on teenage tanning due to be broadcast later this year.

At Cancer Research UK we are deeply concerned about how easily sunbeds can be accessed by children and teenagers. Coin-operated sunbeds and unstaffed salons which offer cheap deals – some around 30p a minute – make using sunbeds extremely appealing to young people, especially girls.

And with the pressure felt by children and teenagers to have a tan, we are concerned that – unless action is taken – young sunbed users will only continue to fuel the dramatic rise in skin cancer rates in the UK.

Research shows that first using a sunbed under the age of 35 increases the risk of developing skin cancer by 75 per cent. This is alongside the irreversible damage caused to the skin. The only way to stop this and protect young children and teenagers is by having a law in place.

We know there’s huge public support for this Bill – 87 per cent want a law to stop under 18s using sunbeds and 90 per cent support sunbed salons being staffed. But although these movements in Parliament are encouraging, a law to stop under 18s using sunbeds is still a long way off.

What we need as a next step is to ensure that MPs show their support and come to the Second Reading of the Bill which takes place in parliament on Friday 29th January.

You can help by asking your MP to support the bill by emailing them using our handy tool.

Laura Dibb, Press Officer at Cancer Research UK