This is not to intentionally to stifle debate around this issue, which is obviously something many feel passionately about (including ourselves). As a charity dedicated to evidence-based science, we absolutely feel that debate and discussion of scientific issues is key to improving cancer treatment and awareness of issues surrounding the disease. That is why we started writing this blog.

Recently, however, we have had to increasingly delete and moderate attempts to post links to websites selling Gc-MAF, and to promote its use to treat cancer. Neither of these is something we’re comfortable with, given the current state of evidence surrounding Gc-MAF. As we’ve repeatedly said above, we believe there are substantial shortcomings with the evidence base around this substance, and until these are clarified, we cannot recommend anyone, anywhere, considers it as a serious treatment option.

We hope you understand, and apologies once again.

Henry, Kat and Ed

We do not directly commission research projects – our funds are awarded through a competitive grant process http://science.cancerresearchuk.org/gapp/ If a researcher wished to carry out work in the UK on Gc-MAF’s potential for treating cancer, they would need to apply to the appropriate Cancer Research UK committee. Their application would then be judged by a panel of national and international experts – as all grant applications are. We will only fund work that is highly competitive, and at the forefront of research into cancer.

Kat

Dear director of Aids Operative Centre.
more than 4 months ago has been possible to notice the publishing, on the scientific Jornal Medical Virology, an article on HIV eradication by Prof. Yamamoto, explaining the way he obtained the Hiv eradication in only 18 weeks by injecting, weekly, 100ng GcMAF, an activating factor of macrophages obtained by the Gc Protein. This is shown by a fully successfull experiment, done in 2002 on 15 assintomatic Hiv+ patients and non anemic one; these patients have been healthy without having a viral feedback (HIV-RNA, HIV-DNA) and immune alterations such as CD4, CD8 and their percentage absolutely normal) in more than seven years (J. Med. Virol. 81:16-26, 2009).

We have been trying to inquire with the help of the associations, specialists and even embassys without having a feedback, particularly:
1 – [authorised ethic committees]
2 – [centres and patients]
3 – [contacts with the authors]
4 – [contacts with the directors of JMV]
….

Now, since the issue continues to cause serious disturbance among all the Hiv+, and we are not in the best possible conditions, we ask to You and to Your Institution, authority of national importance, to clear up the points above, in order to ascertain whether we are faced with a falsely clamorous scientific discovery or a true one.
Certainly we would like to see confirmed the latter one. We are convinced that you would put under exam the GcMAF, a low-cost molecule and of an easy preparation, for further clinical trial in case of the results of Prof Yamamoto would be authentic. This would represent the salvation of millions of Hiv+ people all over the world.
Dispite the disappointment in case the trial is not true, we are greatful to You for having provided to us an answer.
Hopefully in an acceptance of our request, we thank and cordially greet.

An Hiv+ patient.

By the way my daughters chemo was changed and her second round was not as bad. None the less we are also taking extra measures ie. diet no sugars , ozone treatments….ground up flax seed, better water. Maybe zeolite coming next.

Sure hope this Gc-MAF gets off the ground and get rid of chemo……like DDT it should be banned!

Dr Zengh Cui and Mark Willingham

Dr Zengh Cui research makes Yamamoto’s MAF declaration stronger and stronger.

http://www1.wfubmc.edu/tumorbio/srmouse/index.htm

More recent studies, described in the May 8, 2006, Proceedings of the National Academy of Science USA, demonstrated the ability to cure cancer in normal mice by transferring purified immune cells from the cancer-resistant mice. These newer studies show that specific types of innate immune cells, such as macrophages, can migrate to the site of cancer in a normal mice and selectively kill all of the cancer cells without harming normal cells. Such studies suggest that this type of mechanism might one day be able to help design a new strategy for cancer therapy.

Transferable anticancer innate immunity in spontaneous regression/complete resistance mice

Amy M. Hicks*, Gregory Riedlinger†, Mark C. Willingham*, Martha A. Alexander-Miller‡, C. Von Kap-Herr§, Mark J. Pettenati§, Anne M. Sanders*, Holly M. Weir*, Wei Du*, Joseph Kim*, Andrew J. G. Simpson¶, Lloyd J. Old¶,‖, and Zheng Cui*,‖
+Author Affiliations

Departments of *Pathology,
†Cancer Biology, and
‡Microbiology and Immunology, and
§Department of Pediatrics, Section on Medical Genetics, Wake Forest University School of Medicine, Winston-Salem, NC 27157; and
¶Ludwig Institute for Cancer Research, New York, NY 10158
Contributed by Lloyd J. Old, March 28, 2006

Abstract
Spontaneous regression/complete resistance (SR/CR) mice resist very high doses of cancer cells that are lethal to WT mice even at low doses. In this study, we show that this resistance is mediated by rapid infiltration of leukocytes, mostly of innate immunity, in both primary and repeated challenges. Formation of rosettes with infiltrating natural killer cells, neutrophils, and macrophages was required for the subsequent destruction of cancer cells through rapid cytolysis. Highly purified natural killer cells, macrophages, and neutrophils from the SR/CR mice independently killed cancer cells in vitro. The independent killing activity by each subset of effector cells is consistent with the observation that the resistance was abolished by depleting total infiltrating leukocytes but not by depleting only one or two subsets of leukocytes. The resistance was completely transferable to WT recipient mice through SR/CR splenocytes, bone marrow cells, or enriched peritoneal macrophages, either for prevention against subsequent cancer challenges or eradication of established malignancy at distant sites.

There’s lots more information about alternative and complementary treatments on our CancerHelp UK website: http://www.cancerhelp.org.uk/help/default.asp?page=216

I would also strongly recommend that you look at Quackwatch to see if they have anything to say about potential avenues you may be looking at, to see if they could be dangerous, fraudulent or simply ineffective:
http://www.quackwatch.com/00AboutQuackwatch/altseek.html

Best wishes to you and your family,
Kat

But now Im back to square one….I don’t suppose I can get this Gc-MAF.

My daughter’s blood count went down to .3 after her first chemo. Im looking outside the box for sure….she doesn’t want chemo again.

What now….some say go to Mexico others Mushroom extract….some Keelation using Zeolite to purge the body of metals.

Gc-MAF looked like my best bet!

Gc-MAF is not vitamin D. Gc-MAF is a protein made by natural chemical changes to another protein in our bodies called “vitamin D binding protein” . One of vitamin D binding protein’s jobs in the body is to help us absorb vitamin D – but that’s not really important in this story.

As we explained in the post, scientists think that Gc-MAF (naturally produced by the body) activates special white blood cells, macrophages, that then can eat up cancer cells. But these cancer cells can produce another protein called nagalase, which seems to stop the body turning vitamin D binding protein into Gc-MAF. If this is true, this is bad news, as then Gc-MAF can’t activate macrophages, and the cancer can grow.

Dr Yamamoto’s idea is that injecting cancer patients with extra Gc-MAF will compensate for this, causing macrophages to be activated and killing the patient’s cancer cells.

As we’ve explained in the post, this is an intriguing idea, although there are flaws in the research done so far. It’s an interesting avenue of research, but it’s certainly not the 100 per cent cancer cure that is being claimed by some reports.

Kat

Gc-MAF is actually vitamin D3….is that correct

It may boost your immune system by blocking an ensyme called nagalese and let your natural defences ie. white blood cell (macrophages) do the cancer killing?