Over the years, scientists looking inside our cells have found that hundreds of different proteins play a role in the development of cancer.
Some of these have a walk-on part. Others are virtually extras. But there are some that can be thought of as the big “stars” of the field – the George Clooney or Nicole Kidman of cell division, if you like. One of these is called p53, and often billed as “the guardian of the genome.”
But despite years of research, we’re still a long way from knowing exactly how p53 ‘works’. A paper published last week, in top science journal PNAS, is helping change all that. Researchers are working out the protein’s exact 3D structure, and aim to use this knowledge to find out more about this reclusive superstar, and what makes it tick…
Posted by Kat Arney 
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